Pipeline

In-house drug development

Compound/Candidate	Radionuclide	Type	Indication	Discovery	Pre-clinical	First-In-Human	Regulatory	Phase 1
18F-DualFAPi-7 Phase: Discovery Pre-clinical First-In-Human Regulatory Phase 1	18F	β+ (PET)	FAP Expressing Tumors
Radionuclide: 18F Type: β+ (PET) Indication: FAP Expressing Tumors Phase: pre-clinical Description: Target: Fibroblast Activation Protein (FAP) Partner/co-funding: Co-funded by the European Union under the IHI project.
123I-DualFAPi-5 Phase: Discovery Pre-clinical First-In-Human Regulatory Phase 1	123I	γ (SPECT)	FAP Expressing Tumors
Radionuclide: 123I Type: γ (SPECT) Indication: FAP Expressing Tumors Phase: discovery Description: Target: Fibroblast Activation Protein (FAP) Partner/co-funding: Co-funded by the European Union under the EIC Accelerator project
131I-DualFAPi-5 Phase: Discovery Pre-clinical First-In-Human Regulatory Phase 1	131I	β⁻ (therapy)	FAP Expressing Tumors
Radionuclide: 131I Type: β⁻ (therapy) Indication: FAP Expressing Tumors Phase: pre-clinical Description: Target: Fibroblast Activation Protein (FAP) Partner/co-funding: Co-funded by the European Union under the EIC Accelerator project
211At-DualFAPi-5 Phase: Discovery Pre-clinical First-In-Human Regulatory Phase 1	211At	α (therapy)	FAP Expressing Tumors
Radionuclide: 211At Type: α (therapy) Indication: FAP Expressing Tumors Phase: discovery Description: Target: Fibroblast Activation Protein (FAP) Partner/co-funding: Co-funded by the European Union under the IHI project.
18F-FlutraProst Phase: Discovery Pre-clinical First-In-Human Regulatory Phase 1	18F	β+ (PET)	Prostate cancer
Radionuclide: 18F Type: β+ (PET) Indication: Prostate cancer Phase: first-in-human Description: Target: PSMA Partner/co-funding: Co-funded by Eurostars
18F-FlutraTate Phase: Discovery Pre-clinical First-In-Human Regulatory Phase 1	18F	β+ (PET)	NETs
Radionuclide: 18F Type: β+ (PET) Indication: NETs Phase: pre-clinical Description: Target: SSTR/ Octreotate Partner/co-funding: Co-funded by the European Union under the IHI project.
211At-AmbiTag Phase: Discovery Pre-clinical First-In-Human Regulatory Phase 1	211At	α (therapy)	NETs
Radionuclide: 211At Type: α (therapy) Indication: NETs Phase: discovery Description: Target: SSTR/Octreotate Partner/co-funding: Co-funded by Innovation Fund Denmark

Platform Partnerships

Compound/Candidate	Radionuclide	Type	Indication	Discovery	Pre-clinical	First-In-Human	Regulatory	Phase 1
18F-FlutraHexin TVX-01 Phase: Discovery Pre-clinical First-In-Human Regulatory Phase 1	18F	β+ (PET)	Pancreatic cancer
Radionuclide: 18F Type: β+ (PET) Indication: Pancreatic cancer Phase: pre-clinical Description: Target: αvβ6 integrin Partner/co-funding: TRIMT
3BP (211At) Phase: Discovery Pre-clinical First-In-Human Regulatory Phase 1	211At	α (therapy)	Undisclosed
Radionuclide: 211At Type: α (therapy) Indication: Undisclosed Phase: discovery Description: Target: Undisclosed Partner/co-funding: 3B Pharmaceuticals
AmbiTag for Pretargeting Phase: Discovery Pre-clinical First-In-Human Regulatory Phase 1	131I/211At	β⁻ / α (therapy)	Epithelial-derived cancers
Radionuclide: 131I/211At Type: β⁻ / α (therapy) Indication: Epithelial-derived cancers Phase: discovery Description: Target: CD44v6 Partner/co-funding: Co-funded by Eureka under the Eurostars project. Partners includes Pre-TT and Akiram Therapeutics

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